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We agree that youth should never have access to any tobacco products, but this can be achieved without imposing a total prohibition on products that millions of adults choose to use. The law signed by Gov

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27 While head-to-head clinical studies with varenicline have been conducted with the historical cytisine formulation using a 1.5 mg tablet administered in a 25-day downward titration regimen, 2830 no studies, to date, have directly compared varenicline with the novel cytisinicline formulation evaluated in the ORCA program (3 mg tid for 12 weeks), which is currently under regulatory review by the US Food and Drug Administration

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